“The Middlesex” is a novel by American writer of Greek origin Jeffrey Eugenides, written by him in Berlin and awarded the 2003 Pulitzer Prize. One of the greatest American novels that, right after its release, became a modern classic. Eugenides skillfully combines in one novel the principles of an expansive and captivating family saga, a historical novel about America’s rise into a financially ravenous monster, and an adult-coming-of-age story narrated by an unusual child—and later, a teenager. One small genetic change that triggers a deficiency of 5-alpha-reductase—and in the third generation of Americans of Greek origin appears a daughter, Callie, who later turns out to be a boy, Cal. The story of Callie/Cal is a riveting account of living with two bodies and two souls, of an inner tragedy shaped both by the tumultuous and tragic past of the ancestors and by just one tiny change in the hero’s genetic blueprint… It’s a novel that openly speaks about the heavy and frightening—but from which you can’t pull yourself away.