Aerius, one of the worlds of the great Imperium, is ravaged by a monstrous plague epidemic. According to the Oracle’s prophecy, the only thing that can save the dying planet is the Talismán of Likós. But two thousand years ago this artifact was broken into three parts and scattered across the far ends of the galaxy. The Inquisition makes titanic efforts to reunite the Talisman. The Order of the Space Wolves sends a squad of Blood Claws to assist the Inquisitors—among them is the young Ragnar. Battles with orks and tyranids are only a prelude to a fateful battle, the outcome of which will determine the future not only of Aerius, but of the entire Imperium.